diff --git a/flake.lock b/flake.lock
index 99093dcb..5cefc102 100644
--- a/flake.lock
+++ b/flake.lock
@@ -45,11 +45,11 @@
         ]
       },
       "locked": {
-        "lastModified": 1719340949,
-        "narHash": "sha256-YPcmC46g/DgXJhs4ZuXtK7cZgHsfNcWNwvWQ8rRJOkk=",
+        "lastModified": 1719136212,
+        "narHash": "sha256-Z7fAvbFj4wfbJgR5e7NaI48K6SlNbMVTt2jLp8ImOic=",
         "owner": "accentor",
         "repo": "api",
-        "rev": "0706fd5da6d4fde62673067cd5bbbc316e0e809e",
+        "rev": "96d71ff1dff93652a3981fa574ca662102ed555f",
         "type": "github"
       },
       "original": {
@@ -72,11 +72,11 @@
         "systems": "systems"
       },
       "locked": {
-        "lastModified": 1719340957,
-        "narHash": "sha256-qZxy5w2cCR7PgwWxY4wrGj1FGKOJwdtWOcZgG3qNr2M=",
+        "lastModified": 1719136166,
+        "narHash": "sha256-USaTW/G/Aby8P0+gPlQTyYfXV/g9qibIFXXmBiAzumQ=",
         "owner": "accentor",
         "repo": "web",
-        "rev": "9b0cd504d21193ea13eea43d571c9d3763300d7c",
+        "rev": "3a325bc057e6ab25f80e56466b09f748eb9de58e",
         "type": "github"
       },
       "original": {
@@ -213,11 +213,11 @@
         "nixpkgs-stable": "nixpkgs-stable"
       },
       "locked": {
-        "lastModified": 1719363732,
-        "narHash": "sha256-Hlnu6LkDJW5KiWNbcWGK4fpmipiZasd3a6KUPEzRg10=",
+        "lastModified": 1719303695,
+        "narHash": "sha256-SqJTGKtJEzkQdHEUWeMHwQ5vyAg4wE1kRbjTRjzfAUI=",
         "owner": "nix-community",
         "repo": "emacs-overlay",
-        "rev": "2005d1e0260e31e7775349c62eabbcd8ae5bd6e6",
+        "rev": "fd904f28fb1d3d3a3d87db312fac97cb4a146db4",
         "type": "github"
       },
       "original": {
@@ -471,11 +471,11 @@
     },
     "nixpkgs": {
       "locked": {
-        "lastModified": 1719254875,
-        "narHash": "sha256-ECni+IkwXjusHsm9Sexdtq8weAq/yUyt1TWIemXt3Ko=",
+        "lastModified": 1719075281,
+        "narHash": "sha256-CyyxvOwFf12I91PBWz43iGT1kjsf5oi6ax7CrvaMyAo=",
         "owner": "nixos",
         "repo": "nixpkgs",
-        "rev": "2893f56de08021cffd9b6b6dfc70fd9ccd51eb60",
+        "rev": "a71e967ef3694799d0c418c98332f7ff4cc5f6af",
         "type": "github"
       },
       "original": {
@@ -534,11 +534,11 @@
     },
     "nur": {
       "locked": {
-        "lastModified": 1719381117,
-        "narHash": "sha256-/CAMYOC22ZQxrXVmN7UI5N+qtAQGLG1UB3rlQBRb+/c=",
+        "lastModified": 1719337524,
+        "narHash": "sha256-bYp4//+XM+J1Y23sW6VjXAiCHUdq3aqgXue/tVeCxLw=",
         "owner": "nix-community",
         "repo": "NUR",
-        "rev": "6d841b41e480c27660928026a42a2b80690f7a7f",
+        "rev": "37ae43594731d4d801f53dffe465006421c7c292",
         "type": "github"
       },
       "original": {
@@ -751,11 +751,11 @@
         ]
       },
       "locked": {
-        "lastModified": 1719344136,
-        "narHash": "sha256-VckR6cY8uXjG/nHYwzyj49TXdPsMerUYDjG5klkpJ2Q=",
+        "lastModified": 1719138998,
+        "narHash": "sha256-Tw/xJsyh49uzvCDCnIKoJIAGLutSX36FzI72MqJNK8o=",
         "owner": "chvp",
         "repo": "tetris",
-        "rev": "50431b0d76090354185f336a3dc6f2f4efbf5226",
+        "rev": "e8ca69df359f8359afbcec8d77eefdb37c46bd1e",
         "type": "github"
       },
       "original": {
diff --git a/patches/321446.patch b/patches/321446.patch
new file mode 100644
index 00000000..d7a12177
--- /dev/null
+++ b/patches/321446.patch
@@ -0,0 +1,48 @@
+diff --git a/pkgs/development/python-modules/pymilter/default.nix b/pkgs/development/python-modules/pymilter/default.nix
+index 32b7cfcc9bbcd6..6d9338dbc1b90e 100644
+--- a/pkgs/development/python-modules/pymilter/default.nix
++++ b/pkgs/development/python-modules/pymilter/default.nix
+@@ -3,9 +3,8 @@
+   python,
+   buildPythonPackage,
+   fetchFromGitHub,
+-  fetchpatch,
+   libmilter,
+-  bsddb3,
++  berkeleydb,
+   pydns,
+   iana-etc,
+   libredirect,
+@@ -14,29 +13,22 @@
+ 
+ buildPythonPackage rec {
+   pname = "pymilter";
+-  version = "1.0.5";
++  version = "1.0.6";
+   format = "setuptools";
+ 
+   src = fetchFromGitHub {
+     owner = "sdgathman";
+     repo = pname;
+     rev = "${pname}-${version}";
+-    hash = "sha256-gZUWEDVZfDRiOOdG3lpiQldHxm/93l8qYVOHOEpHhzQ=";
++    hash = "sha256-plaWXwDAIsVzEtrabZuZj7T4WNfz2ntQHgcMCVf5S70=";
+   };
+ 
+   buildInputs = [ libmilter ];
+   nativeCheckInputs = [ pyasyncore ];
+   propagatedBuildInputs = [
+-    bsddb3
++    berkeleydb
+     pydns
+   ];
+-  patches = [
+-    (fetchpatch { # https://github.com/sdgathman/pymilter/pull/57
+-      name = "Remove-calls-to-the-deprecated-method-assertEquals";
+-      url = "https://github.com/sdgathman/pymilter/commit/1ead9028fc63ae3ec6ea3b0c438e6ed088a2b20e.patch";
+-      hash = "sha256-/5LlDR15nMR3l7rkVjT3w4FbDTFAAgNdERWlPNL2TVg=";
+-    })
+-  ];
+ 
+   preBuild = ''
+     sed -i 's/import thread/import _thread as thread/' Milter/greylist.py